Relates to tumour types | Title of Research | Description | More information |
---|---|---|---|
Glioma Glioblastoma Anaplastic oligodendroglioma Anaplastic glioma Anaplastic astrocytoma |
Imaging in Transforming Gliomas (Study ID: 17381) | Gliomas are the commonest type of primary brain tumours accounting for approximately 70% of primary brain tumours in adults. Gliomas can be classified into two main... read more | |
Glioma Glioblastoma Astrocytoma Anaplastic oligodendroglioma Anaplastic glioma Anaplastic astrocytoma |
MR characterisation of invasive phenotypes in GBMs (Study ID: 8596) | High grade gliomas are aggressive tumours that are usually rapidly fatal despite intensive treatment. If we could identify patients with limited spread, they might be... read more | |
Schwannoma Pituitary Paediatric Brain metastases Neuroblastoma oligoastrocytoma Ependymoma Meningioma Medulloblastoma Glioma Glioblastoma Astrocytoma Anaplastic oligodendroglioma Anaplastic glioma Anaplastic astrocytoma |
VoxTox - Linking radiation dose at the voxel level with toxicity (Study ID: 13716) | An observational study to collect detailed information about side effects for patients undergoing image-guided intensity-modulated radiotherapy to the head and neck,... read more | |
Schwannoma Pituitary Paediatric Neuroblastoma oligoastrocytoma Ependymoma Meningioma Medulloblastoma Glioma Astrocytoma |
MOT – Identification and validating molecular targets in low grade brain tumours (Study ID: 16948) | A laboratory study using surplus tissue from all low grade brain tumours to discover and validate new molecular drug targets. read more | |
Glioblastoma Glioma |
Imaging Hypoxia in Cerebral Tumours (Study ID: 20704) | This is a study which will involve patients with a recently discovered brain lesion compatible with diagnosis of glioblastoma multiforme (GBM) and/or recurrent grade... read more | |
Glioma |
VINILO – A trial of vinblastine and nilotinib for children and young people with a brain tumour (Study ID: 31853) | Low grade gliomas (LGG) are the most frequent brain tumour in children. More than 50% of these tumours will progress within the first 5 years and need further... read more | |
Paediatric Glioma |
Pomalidomide (CC-4047) Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumours (Study ID: 34954) | A Phase 2 study that will assess the efficacy, safety and tolerability of pomalidomide in children and young adults aged 1 to < 21 years with recurrent or progressive... read more | |
Glioma |
MISSION: GliomaS – A physiological exploratory study to assess tissue structure and metabolism in Glioma using sodium-23 Magnetic Resonance Imaging (23Na-MRI) (Study ID: 33936) | Cancer cells undergo a change in structure and an increase in metabolism that can be imaged using Sodium-23 magnetic resonance imaging (23Na-MRI), Hyperpolarized... read more | |
Schwannoma Pituitary Brain metastases Neuroblastoma oligoastrocytoma Ependymoma Meningioma Medulloblastoma Glioma Glioblastoma Astrocytoma Anaplastic oligodendroglioma Anaplastic glioma Anaplastic astrocytoma |
Wrist Worn Trackers for monitoring physical activity in brain tumour patients (Study ID: 38629) | Most patient with brain tumours develop functional disturbance (weakness, balance problems, etc.) as part of their illness, and report fatigue as being a significant... read more | |
Schwannoma Pituitary Brain metastases Neuroblastoma oligoastrocytoma Ependymoma Meningioma Medulloblastoma Glioma Glioblastoma Astrocytoma Anaplastic oligodendroglioma Anaplastic glioma Anaplastic astrocytoma |
MOLGEN – Molecular Genetics of Adverse Drug Reactions (Study ID: 8630) | Adverse drug reactions (ADR's) are a common cause of drug-related morbidity and may account for about 6.5% of all hospital admissions. A meta-analysis of studies... read more | |
Schwannoma Pituitary Brain metastases Neuroblastoma oligoastrocytoma Ependymoma Meningioma Medulloblastoma Glioma Glioblastoma Astrocytoma Anaplastic oligodendroglioma Anaplastic glioma Anaplastic astrocytoma |
Establishing multipotent stem cell lines from CNS tumours (Study ID: 32706) | A striking feature of some central nervous system (CNS) tumours is the presence of cell types indicative of mixed neural/glial and mesodermal/mesenchymal (e.g.... read more | |
Anaplastic astrocytoma Anaplastic glioma Anaplastic oligodendroglioma Astrocytoma Glioblastoma Glioma Medulloblastoma Meningioma Ependymoma oligoastrocytoma Neuroblastoma Brain metastases Pituitary Schwannoma |
Hyperpolarised 13C-Pyruvate MRI study (Study ID: 34177) | Metabolic changes related to disease are the precursor to anatomical changes in tissues. Currently our imaging methods routinely used in clinical practice look at the... read more | |
Anaplastic glioma Anaplastic oligodendroglioma Glioblastoma Glioma |
Glutamate Dysfunction in Gliomas, V1.0 (Study ID: 35345) | Seizures are a frequent and serious problem for patients with brain tumours and are often not controlled with current best medical and surgical treatments. There are... read more | |
Anaplastic glioma Anaplastic oligodendroglioma Glioblastoma Glioma |
Tissue-type MRI of brain tumours (Study ID: 35807) | Gliomas are the most common primary brain tumour. They can be “high-grade†with rapid growth and short patient survival times, or “low-gradeâ€... read more | |
Anaplastic astrocytoma Anaplastic glioma Anaplastic oligodendroglioma Astrocytoma Glioblastoma Glioma Medulloblastoma Meningioma Ependymoma oligoastrocytoma Neuroblastoma Brain metastases Pituitary Schwannoma |
Identifying the origin of circulating DNA to detect and diagnose neuro (Study ID: 36279) | Damaged and dying cells release DNA into the circulation. This circulating, cell-free DNA (cfDNA) can be easily detected in blood and other bodily fluids such as... read more | |
Anaplastic astrocytoma Anaplastic glioma Anaplastic oligodendroglioma Astrocytoma Glioblastoma Glioma Medulloblastoma Meningioma Ependymoma oligoastrocytoma Neuroblastoma Brain metastases Pituitary Schwannoma |
Harnessing plasticity to treat brain tumours (Study ID: 37315) | Brain tumours are hard to treat. They are not very sensitive to chemotherapy and radiotherapy. The main therapy is brain surgery to remove the tumour. Even if the... read more | |
Anaplastic astrocytoma Anaplastic glioma Anaplastic oligodendroglioma Astrocytoma Glioblastoma Glioma Medulloblastoma Meningioma Ependymoma oligoastrocytoma Neuroblastoma Brain metastases Pituitary Schwannoma |
HSI Neuro Phantom (Study ID: 38815) | Successful neurosurgery to remove brain tumours depends on achieving maximal safe tumour removal; avoiding damaging sensitive areas that undertake vital functions and... read more | |
Schwannoma Pituitary Brain metastases Neuroblastoma oligoastrocytoma Ependymoma Meningioma Medulloblastoma Glioma Glioblastoma Astrocytoma Anaplastic oligodendroglioma Anaplastic glioma Anaplastic astrocytoma |
BT-LIFE – Brain Tumours, Lifestyle Interventions, and Fatigue Evaluations (Study ID: 38936) | 'BT-LIFE' stands for “Brain Tumours, Lifestyle Interventions, and Fatigue Evaluation." We aim to see if it is feasible to treat fatigue without using drugs, in... read more | |
Glioma |
Biomede – Biological Medicine for Diffuse Intrinsic Pontine Glioma (study ID: 33023) | Biomede is an international, multicenter, randomised, open-label, adaptive, phase II trial of treatment for Diffuse Intrinsic Pontine Glioma (DIPG). This trial... read more |